OFM - Open flow microperfusion
OFM is a probe-based method that is used to evaluate the pharmacokinetics and pharmacodynamics of drugs directly in skin, adipose and brain tissue. The use of the OFM probes allows small amounts of interstitial fluid (ISF) to be collected from target tissues for analysis. OFM is particularly suitable for the analysis of large, lipophilic substances.
We use OFM in clinical and preclinical studies.