Health
Dr Christoph Magnes
Health
Neue Stiftingtalstraße 2
8010 Graz
Österreich
publications
- Tachycardiomyopathy entails a dysfunctional pattern of interrelated mitochondrial functions
- Effect of Liraglutide Treatment on Whole Body Glucose Fluxes in C-peptide Positive Type 1 Diabetes During Hypoglycaemia
- The effect of spermidine on autoimmunity and beta cell function in NOD mice
- Insights into the Composition of a Co-Culture of 10 Probiotic Strains (OMNi BiOTiC ® AAD10) and Effects of Its Postbiotic Culture Supernatant
- Metabolic profiling of attached and detached metformin and 2-deoxy-D-glucose treated breast cancer cells reveals adaptive changes in metabolome of detached cells
- Dietary spermidine improves cognitive function
- Pharmacokinetics and Pharmacodynamics of Three Different Formulations of Insulin Aspart: A Randomized, Double-Blind, Crossover Study in Men With Type 1 Diabetes
- A novel human ex vivo skin model to study early local responses to burn injuries
- A novel human ex vivo skin model to study early local responses to burn injuries
- Spermidine Supplementation and Voluntary Activity Differentially Affect Obesity-Related Structural Changes in the Mouse Lung
- Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans
- N-acetylaspartate availability is essential for juvenile survival on fat-free diet and determines metabolic health
- Open flow microperfusion (OFM) – a tool for in vivo metabolic profiling of adipose tissue
- Feasibility of rapidly assessing reactive impurities mediated excipient incompatibility using a new method: A case study of famotidine-PEG system
- Validation of the doubly-labelled water method to determine total energy expenditure
- Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans
- Targeting the H3K4 Demethylase KDM5B Reprograms the Metabolome and Phenotype of Melanoma Cells
- N-acetylaspartate Pathway Is Nutrient Responsive and Coordinates Lipid and Energy Metabolism in Brown Adipocytes
- The flavonoid 4,4'-dimethoxychalcone promotes autophagy-dependent longevity across species
- Progesterone-associated arginine decline at luteal phase of menstrual cycle and associations with related amino acids and nuclear factor kB activation
- Development of a LC-MS method for quantification of six common pharmaceuticals in OFM samples
- Metabolic phenotyping of first degree relatives of patients with type 1 diabetes
- Metabolomics analysis of rats subjected to hemorrhagic/traumatic shock and resuscitation
- Dietary spermidine for lowering high blood pressure
- Cardioprotection and lifespan extension by the natural polyamine spermidine
- Adipocyte Glucocorticoid Receptor Deficiency Attenuates Aging- And HFD-Induced Obesity and Impairs the Feeding-Fasting Transition
- Determination of (2)H-enrichment of rat brain interstitial fluid and rat plasma by headspace-gas-chromatography - quadrupole-mass-spectrometry.
- An untargeted metabolomics approach to characterize short-term and long-term metabolic changes after bariatric surgery
- Cognitive impairment by antibiotic-induced gut dysbiosis: Analysis of gut microbiota-brain communication
- Susceptibility of Different Mouse Wild Type Strains to Develop Diet-Induced NAFLD/AFLD-Associated Liver Disease.
- Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice.
- N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes
- Cognitive Impairment by Antibiotic-Induced Gut Dysbiosis: Analysis of Gut Microbiota-Brain Communication
- Matrix removal in state of the art sample preparation methods for serum by charged aerosol detection and metabolomics-based LC-MS
- GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis
- Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae.
- Identification of novel metabolic interactions controlling carbon flux from xylose to ethanol in natural and recombinant yeasts
- We have the analyte – but where is the dross?
- IPO – Automated optimization of XCMS parameters
- Quantifying Vitamin D and its metabolites by LC/orbitrap MS
- Novel method for determining eicosanoids in the interstitial fluid of psoriatic skin
- An untargeted metabolomics approach highlights short-term and long-term effects of bariatric surgery in humans
- IPO: A Tool for automated XCMS Parameter Optimization
- Endogenous glucose production during hypoglycemia in patients with newly diagnosed and long-standing type 1 diabetes
- Metabolomics - What it is and how it helps
- IPO: A Tool for Automated Optimization Untargeted Metabolomics LC-MS Data Processing
- Modeling non-hereditary mechanisms of Alzheimer disease during apoptosis in yeast
- Entwicklung und Validierung einer UHPLC-MS/MS Methode zur Ermittlung der Pharmakokinetik von antiviralen Aciclovir-Cremen
- Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin
- A data driven approach to explore the link between metabolomics and diabetes relevant outcomes after bariatric surgery
- Increasing the Reliability of Untargeted Metabolomics by Using Natural Stable 13C Isotopes
- An analytical method (UHPLC-MS/MS) to determine the pharmacodynamic behavior of the topically applied antiviral
- We have the analyte – but where is the dross?
- Autophagy extends lifespan via vacuolar acidification
- A histone point mutation that switches on autophagy
- Acetyl-coenzyme A: A metabolic master regulator of autophagy and longevity
- Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae
- Nucleocytosolic Depletion of the Energy Metabolite Acetyl-Coenzyme A Stimulates Autophagy and Prolongs Lifespan
- Polyamines in biological samples: Rapid and robust quantification by solid-phase extraction online-coupled to liquid chromatography-tandem mass spectrometry
- Regulation of Autophagy by Cytosolic Acetyl-Coenzyme A
- Clinical applicability of dOFM devices for dermal sampling
- Determination of the trypanocidal drug melarsoprol and its conversion products in biological fluids with HPLC-ICPMS/ESMS
- Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner
- Spermidine promotes mating and fertilization efficiency in model organisms
- Remodeling of lipid droplets during lipolysis and growth in adipocytes.
- Alterations in Lipid Metabolism Mediate Inflammation, Fibrosis, and Proliferation in a Mouse Model of Chronic Cholestatic Liver Injury
- Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
- Arsenosugar phospholipids and arsenic hydrocarbons in two species of brown macroalgae
- Dermal open-flow microperfusion as a novel technique for in vivo measurement of dermal interstitium
- Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling
- Spermidine promotes mating and fertilization efficiency in model organisms.
- Absolute/relative bioavailability and metabolism of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides (tetraenes) after intravenous and oral single doses to rats.
- The propeptide of yeast cathepsin D inhibits programmed necrosis.
- Novel catheters for in vivo research and pharmeceutical trials providing direct access to extracellular space of target tissues
- Efficient phagocytosis requires triacylglycerol hydrolysis by adipose triglyceride lipase.
- A new strategy for the sensitive and simultaneous analysis of human insulin and insulin analogues using LC/MS² in combination with a tailored sample clean-up procedure
- Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling
- Online SPE-LC/FTMS (Orbitrap) Technique for Metabolite Profiling (Acyl CoAS)
- Profiling of Acyl CoAs in Biological Tissues using Online SPE-LC-FTMS (Orbitrap)
- Induction of autophagy by spermidine promotes longevity.
- Ring-Opening Metathesis Polymerisation-derived Capillary Monoltihs: Versatile Analytical Tools for Modern Biomedical Research
- Ultrafiltration as a purification step in sample preparation for LC/MS² analysis of insulin in serum
- A novel minimally-invasive approach for investigations into skin barrier function and percutaneous drug penetration
- A Validated Analytical Method for Quantification and Identification of Coenzyme-A Activated Compounds in Tissue Samples by online SPE-LC/MS/MS
- A validated analytical method for the dermination of L-Cystine, N-Acetyl-L-Cysteine, L-Cysteine and rearrangement products in amino acid solutions by LC/MS/MS
- Functionalization of ROMP-derived monolithic capillary columns and their chromatographic properties
- Insulin glulisine, insulin lispro and regular human insulin show comparable end-organ metabolic effects: an exploratory study.
- Ring-opening metathesis polymerization-derived monolithic capillary columns for high-performance liquid chromatography: downscaling and application in medical research.
- Sensitive insulin analysis in interstitial fluid: Influence of mobile phase additives on insulin B chain loading efficiency in CAP-HPLC/MS
- Strategies for sensitive peptide detection in brain homogenate using LC/MS for the purpose of blood-brain-delivery testing
- Validated comprehensive analytical method for quantification of coenzyme A activated compounds in biological tissues by online solid-phase extraction LC/MS/MS.
- Rapid online-SPE-MS/MS method for ketoprofen determination in dermal interstitial fluid samples from rats obtained by microdialysis or open-flow microperfusion.
- New strategy for insulin andinsulin analogs quantification – MRM detection for insulin B chain
- Norbornene-based monolithic capillary columns for clinical research
- Proportional dose-response relationship and lower within-patient variability of insulin detemir and NPH insulin in subjects with type 1 diabetes mellitus.
- Rapid online-SPE-MS/MS method for ketoprofen determination in dermal interstitial fluid samples from rats obtained by microdialysis or open-flow microperfusion.
- ROMP-based monolithic capillary columns as ESI-Interface for fast and sensitive LC-MS analysis
- Romp-based monolithic capillary columns for ion-exchange liquid chromatography
- Validated Comprehensive Analytical Method for Quantification of Coenzyme-A Activated Compounds in Biological Tissues by Triple Quadrupol LC/MS/MS
- Identification of coenzyme A activated substances by accurate mass determination using ESI triple quadrupole mass spectrometry
- A Sensitive HPLC/MS/MS Method for the Determination of Short- and Long Chain Fatty Acyl-CoAs in Biological Tissues
- A double-blind, randomized, dose-response study investigating the pharmacodynamic and pharmacokinetic properties of the long-acting insulin analog detemir.
- Evaluation of ring-opening metathesis polymerization (ROMP)-derived monolithic capillary high performance liquid chromatography columns.
- LC/MS/MS method for quantitative determination of long-chain fatty acyl-CoAs.
- The interstitium: an analytical challenge
- Strategies for Quantification of Insulin and Insulin Analogues by LC MS/MS
- Monolithic Stationary Phases Prepared by Ring-Opening Metathesis Polymerisation: Influence of Different Polymerisation Parameters on Separation Performance
- Mögliche Hepatoselektivität von Insulin Detemir im Vergleich zu NPH Insulin in Patienten mit Typ-1-Diabetes