Health
Dr Katrin Tiffner
Health
Neue Stiftingtalstraße 2
8010 Graz
Österreich
publications
- Dermal open flow microperfusion for PK-based clinical bioequivalence studies of topical drug products
- Comparative in Vitro Release Testing (IVRT) of Acyclovir Products
- A novel human ex-vivo burn model and the local cooling effect of a bacterial nanocellulose-based wound dressing
- Variability of Skin Pharmacokinetic Data: Insights from a Topical Bioequivalence Study Using Dermal Open Flow Microperfusion
- A novel human ex-vivo burn model and the local cooling effect of a bacterial nanocellulose-based wound dressing
- Bacterial nanocellulose-based wound dressings provide a clinically relevant cooling effect on burn injuries wound repair regen
- Clinical Study Design to Evaluate Whether the Systemic Bioavailability of Topical Drugs May Influence the Assessment of Local Dermal Pharmacokinetics by Dermal Open Flow Microperfusion (dOFM)
- Dermal pharmacokinetic endpoint studies to evaluate bioequivalence of topically applied lidocaine and prilocaine drug products
- Variability of topical penetration data from Dermal Open Flow Microperfusion might be attributed to variability in skin barrier function and follicular penetration
- Dermal open flow microperfusion: Sampling of interstitial fluid directly from the dermis for pharmacokinetic and pharmacodynamic evaluations
- Bioequivalence of Topical Products in Excised Human Skin Assessed with dermal Open Flow Microperfusion
- Variability of topical penetration data: what do we learn from a bioequivalence study using dermal open flow microperfusion
- Assessment of skin permeability to topically applied drugs by skin impedance and admittance
- Local Inflammatory Response after Topically Applied Burn Stimuli Investigated in Excised Human Skin
- In Vivo Dermal Open Flow Microperfusion: Understanding and Controlling Sources of Variability to Evaluate Topical Bioequivalence
- A Comprehensive Approach to Qualify and Validate the Essential Parameters of an In Vitro Release Test (IVRT) Method for Acyclovir Cream, 5%
- Quantification of Basal Insulin Peglispro and Human Insulin in Adipose Tissue Interstitial Fluid by Open-Flow Microperfusion.
- Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence
- Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence
- Comparative In Vitro Release Tests (IVRT) Of Seven Topical Acyclovir Products Using A Validated IVRT Method With A Vertical Diffusion Cell (VDC) Apparatus
- Open Flow Microperfusion as Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence
- Comparative In Vitro Release of Six Different Topical Acyclovir Products Using a Vertical Diffusion Cell (VDC) Apparatus
- Open Flow Microperfusion as Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence
- Secukinumab Distributes into Dermal Interstitial Fluid of Psoriasis Patients as Demonstrated by Open Flow Microperfusion
- Characterization of TEWL and Skin Impedance in a Clinical Study Measuring Acyclovir Permeation by Dermal Open Flow Microperfusion
- Open flow microperfusion for bioequivalence testing of topical drug in the dermis
- An analytical method (UHPLC-MS/MS) to determine the pharmacodynamic behavior of the topically applied antiviral
- Secukinumab, a novel anti-IL-17A antibody, can be quantified in skin after a single dose by dermal open flow microperfusion (dOFM)
- The anti IL-17A IgG1 antibody distributes in dermal interstitial fluid as demonstrated by using dermal open flow microperfusion after a single 300 mg subcutaneous administration; assessment in healthy volunteers and patients with moderate-to-severe plaque
- Absolute levels of the novel anti-IL-17A antibody, secukinumab, in skin can be quantified by dermal open flow microperfusion (dOFM)
- Open Flow Microperfusion: An Alternative Method to Microdialysis?
- Skin impedance measurements support ex-vivo penetration studies for topical applied drugs