Use Cases

Bioavailability assessment of monoclonal antibodies

Detailed spatial- and time-resolved pharmacokinetic data obtained via aOFM enhance bioavailability prediction of subcutaneously delivered monoclonal antibodies (mAbs).

Pharmacokinetics of Topical Analgesics

Drug transport through skin and adipose into muscle tissue after application of an analgesic patch.

cOFM xenograft

Atraumatic access to brain tumours for the development of personalised cancer therapies

PK of nanoformulated drugs in the brain

cOFM was successfully used to compare the transport of GLA in different nanoformulations across the blood-brain barrier

Therapeutic antibody in the skin

dOFM was successfully used to measure a therapeutic antibody and inflammatory markers in healthy and lesional skin of patients with psoriasis.

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