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DI Dr. Thomas Altendorfer-Kroath

Research group

HEALTH:

Biomedical Tissue Monitoring

Phone number

+43 316 876-4119

E-mail

Thomas.Kroath@joanneum.at

Address

Neue Stiftingtalstraße 2, 8010, Graz
+43 316 876-4000
health@joanneum.at

Publications

Health
2025

Cerebral open flow microperfusion (cOFM)-HILIC-HRMS platform for in vivo and in situ monitoring of tumor microenvironment in glioblastoma

Authors Fernanda Monedeiro, Denise Schimek, Eva-Maria Prugger, Thomas Altendorfer-Kroath, Elmar Zügner, Christoph Magnes
Cerebral open flow microperfusion (cOFM)-HILIC-HRMS platform for in vivo and in situ monitoring of tumor microenvironment in glioblastoma
Health
2024

Implementation and validation of a UHPLC-MS/MS method for quantification of the endocannabinoids AEA and 2-AG in cerebral interstitial fluid and plasma

Authors Weiermeier T, Svehlikova E, Magnes C, Boulgaropoulos B, Altendorfer-Kroath T, Hummer J, Eberl A
Implementation and validation of a UHPLC-MS/MS method for quantification of the endocannabinoids AEA and 2-AG in cerebral interstitial fluid and plasma
Health
2024

Targeted nanoliposomes to improve enzyme replacement therapy of Fabry disease

Authors Judit Tomsen-Melero, Marc Moltó-Abad, Josep Merlo-Mas, Zamira V Díaz-Riascos, Edgar Cristóbal-Lecina, Andreu Soldevila, Thomas Altendorfer-Kroath, Dganit Danino, Inbal Ionita, Jan Skov Pedersen, Lyndsey Snelling, Hazel Clay, Aida Carreño, José L Corchero, Daniel Pulido, Josefina Casas, Jaume Veciana, Simó Schwartz Jr, Santi Sala, Albert Font, Thomas Birngruber, Miriam Royo, Alba Córdoba, Nora Ventosa, Ibane Abasolo, Elisabet González-Mira
Targeted nanoliposomes to improve enzyme replacement therapy of Fabry disease
Health
2023

Quantification of the Therapeutic Antibody Ocrelizumab in Mouse Brain Interstitial Fluid Using Cerebral Open Flow Microperfusion and Simultaneous Monitoring of the Blood–Brain Barrier Integrity

Authors Altendorfer-Kroath, Thomas; Hummer, Joanna; Kollmann, Denise; Boulgaropoulos, Beate; Raml, Reingard; Birngruber, Thomas
Quantification of the Therapeutic Antibody Ocrelizumab in Mouse Brain Interstitial Fluid Using Cerebral Open Flow Microperfusion and Simultaneous Monitoring of the Blood–Brain Barrier Integrity
Health
2023

Atraumatic access to human glioblastoma in a xenograft animal model by cerebral open flow microperfusion

Authors Altendorfer-Kroath, Thomas; Asslaber, Martin; Hummer, Joanna; Boulgaropoulos, Beate; Prietl, Barbara; Pieber, Thomas R.; Bernhart, Eva; Birngruber, Thomas
Atraumatic access to human glioblastoma in a xenograft animal model by cerebral open flow microperfusion
Health
2023

In vivo monitoring of brain pharmacokinetics and pharmacodynamics with cerebral open flow microperfusion

Authors Altendorfer‐Kroath, Thomas; Hummer, Joanna; Birngruber, Thomas
In vivo monitoring of brain pharmacokinetics and pharmacodynamics with cerebral open flow microperfusion
Health
2019

Comparison of cerebral Open Flow Microperfusion and Microdialysis when sampling small lipophilic and small hydrophilic substances

Authors Altendorfer-Kroath, Thomas; Schimek, Denise; Eberl, Anita; Rauter, Günther; Ratzer, Maria; Raml, Reingard; Sinner, Frank; Birngruber, Thomas
Comparison of cerebral Open Flow Microperfusion and Microdialysis when sampling small lipophilic and small hydrophilic substances
Health
2019

Insulin distribution in human adipose tissue via a novel insulin infusion catheter

Authors Altendorfer‐Kroath, Thomas; Schwingenschuh, Simon; Schondorff-Kruse, Pernelle; Heschel, Matthias; Sinner, Frank; Birngruber, Thomas
Insulin distribution in human adipose tissue via a novel insulin infusion catheter
Health
2019

Cerebral Open Flow Microperfusion to Monitor Drug Transport Across the Blood‐Brain Barrier

Authors Hummer, Joanna; Altendorfer‐Kroath, Thomas; Birngruber, Thomas
Cerebral Open Flow Microperfusion to Monitor Drug Transport Across the Blood‐Brain Barrier
Health
2018

Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice

Authors Kleinert, Maximilian; Kotzbeck, Petra; Altendorfer‐Kroath, Thomas; Birngruber, Thomas; Tschöp, Matthias H.; Clemmensen, Christoffer
Time-resolved hypothalamic open flow micro-perfusion reveals normal leptin transport across the blood–brain barrier in leptin resistant mice
Health
2016

Determination of (2)H-enrichment of rat brain interstitial fluid and rat plasma by headspace-gas-chromatography - quadrupole-mass-spectrometry

Authors Eberl, A; Altendorfer‐Kroath, Thomas; Kollmann, D; Birngruber, Thomas; Sinner, F; Raml, R; Magnes, Christoph
Determination of (2)H-enrichment of rat brain interstitial fluid and rat plasma by headspace-gas-chromatography - quadrupole-mass-spectrometry
Health
2014

Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx,®/Doxil®—A Cerebral Open Flow Microperfusion Pilot Study

Authors Birngruber, Thomas; Raml, Reingard; Gladdines, Werner; Gatschelhofer, Christina; Gander, Edgar; Ghosh, Arijit; Kroath, Thomas; Gaillard, Pieter J; Pieber, Thomas R; Sinner, Frank
Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx,®/Doxil®—A Cerebral Open Flow Microperfusion Pilot Study
Health
2014

Assessment of blood-brain barrier function and the neuroinflammatory response in the rat brain by using cerebral open flow microperfusion (cOFM).

Authors Ghosh, Arijit; Birngruber, Thomas; Sattler, Wolfgang; Kroath, Thomas; Ratzer, Maria; Sinner, Frank M.; Pieber, Thomas R
Assessment of blood-brain barrier function and the neuroinflammatory response in the rat brain by using cerebral open flow microperfusion (cOFM).
Health
2014

Long-Term Implanted cOFM Probe Causes Minimal Tissue Reaction in the Brain

Authors Birngruber, Thomas; Ghosh, Arijit; Hochmeister, Sonja; Asslaber, Martin; Kroath, Thomas; Pieber, Thomas R.; Sinner, Frank
Long-Term Implanted cOFM Probe Causes Minimal Tissue Reaction in the Brain
Health
2013

Cerebral open flow microperfusion: a new in vivo technique for continuous measurement of substance transport across the intact blood-brain barrier.

Authors Birngruber, Thomas; Ghosh, Arijit; Perez-Yarza, Veronica; Kroath, Thomas; Ratzer, Maria; Pieber, Thomas R; Sinner, Frank M.
Cerebral open flow microperfusion: a new in vivo technique for continuous measurement of substance transport across the intact blood-brain barrier.
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