Evidence-based therapy for hypertrophic scars
RUNNING TIME:
01/2019
—
12/2020
Total project duration:
2 Jahre
The project
Hypertrophic scars are usually bulging, reddened and raised above the surrounding skin level; patients often complain of severe itching and pain. There is therefore an urgent need to establish a representative model in order to better understand the development processes of hypertrophic scars and to further develop existing treatment options.
Our activities in the project
As part of an in-house research project, a model for the development of hypertrophic scars was established and characterised.
Research groups
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Auftraggeber
Projekt der Eigenforschung
Projektpartner
Project details
Scarring is a physiological response of the body to deeper skin injuries. Ideally, scars develop flat and are barely visible. However, pathological excessive scarring - so-called hypertrophic scars - can occur, which often represent not only an aesthetic but also a functional problem for those affected. Hypertrophic scars are usually bulging, reddened, raised from the surrounding skin level and patients often complain of severe itching and pain.
This excessive scarring is sometimes caused by an overproduction of collagen. The pathophysiology of hypertrophic scars is not yet fully understood - which in turn explains the lack of effective and evidence-based treatment concepts. There is therefore an urgent need to establish a representative model in order to better understand the development processes of hypertrophic scars and to further develop existing treatment options.
This is where we come in and develop preclinical models for hypertrophic scars, investigate the underlying pathophysiology and thus offer the opportunity to optimise existing therapies and develop new therapeutic approaches with the help of these models.
