Publikationen

Health

Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling

Beteiligte Autoren der JOANNEUM RESEARCH:

DI DI Dr. Franz Feichtner; DI Dr. Manfred Bodenlenz; DIⁱⁿ Dr.ⁱⁿ Karin Pickl; Mag. Dr. Christoph Magnes; Maria Ratzer, MA; Priv.-Doz. DI Dr. Frank Sinner; Univ.-Prof. Dr.med.univ. Thomas Pieber

Autor*innen:

Bodenlenz, Manfred; Höfferer, Christian; Magnes, Christoph; Schaller-Ammann, Roland; Schaupp, Lukas; Feichtner, Franz; Ratzer, Maria; Pickl, Karin; Sinner, Frank; Wutte, Andrea; Korsatko, Stefan; Köhler, Gerd; Legat, Franz J.; Benfeldt, Eva M.; Wright, Andrew M.; Neddermann, Daniel; Jung, Thomas; Pieber, Thomas R

Abstract:

Methodologies for continuous sampling of lipophilic drugs and high-molecular solutes in the dermis are currently lacking. We investigated the feasibility of sampling a lipophilic topical drug and the locally released biomarker in the dermis of non-lesional and lesional skin of psoriatic patients over 25h by means of membrane-free dermal open-flow microperfusion probes (dOFM) and novel wearable multi-channel pumps.

Titel:

Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling

Seiten:

635–641

Publikationsdatum

2012-08

Publikationsreihe

Nummer

Beitrag

ISSN

09396411

Proceedings

European Journal of Pharmaceutics and Biopharmaceutics

Weitere Dateien und links

http://linkinghub.elsevier.com/retrieve/pii/S0939641112001051 http://www.ncbi.nlm.nih.gov/pubmed/22554768 https://linkinghub.elsevier.com/retrieve/pii/S0939641112001051

DOI-Url:

https://www.doi.org/ 10.1016/j.ejpb.2012.04.009

Jahr/Monat:

2012

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Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling

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Dermal PK/PD of a lipophilic topical drug in psoriatic patients by continuous intradermal membrane-free sampling

Publikationsreihe

Ähnliche Publikationen

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An Examination of Soil Crusts on the Floor of Jezero Crater, Mars

A real-time algorithm for human action recognition in RGB and thermal video

WONACH SUCHEN SIE?

Miteinander zukunftsrelevant

KONTAKTJOANNEUM RESEARCHForschungsgesellschaft mbH

Services

Links

KONTAKT
JOANNEUM RESEARCH
Forschungsgesellschaft mbH