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Dr.in Reingard Raml

Funktion

Stv. Forschungsgruppenleitung

Forschungsgruppe

HEALTH:

Bioanalytik und Metabolomics

Telefon

+43 316 876-4212

E-Mail

Reingard.Raml@joanneum.at

Adresse

Neue Stiftingtalstraße 2, 8010, Graz
+43 316 876-4000
health@joanneum.at

Publikationen

Health
2025

Open flow microperfusion to assess local drug concentrations in the buccal mucosa

Autor*innen: Laura Wiltschko, Paula Fischer, Simon Schwingenschuh, Reingard Raml, Georg Raber, Thomas Birngruber, Eva Roblegg
Open flow microperfusion to assess local drug concentrations in the buccal mucosa
Health
2025

Impact of protein binding on drug sampling by microdialysis and open flow microperfusion

Autor*innen: Laura Wiltschko, Simon Schwingenschuh, Peter Reisenegger, Stephanie Eder, Manfred Bodenlenz, Eva Roblegg, Thomas Birngruber, Reingard Raml
Impact of protein binding on drug sampling by microdialysis and open flow microperfusion
Health
2025

Inkjet-printed drug-loaded temporary tattoos for personalized pediatric pain treatment

Autor*innen: Eder, Simone and Wolfgang, Matthias and Zettl, Manuel and Wiltschko, Laura and Raml, Reingard and Roblegg, Eva and Spoerk, Martin
Inkjet-printed drug-loaded temporary tattoos for personalized pediatric pain treatment
Health
2024

Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model

Autor*innen: Bodenlenz M, Yeaho T, Berstein G, Mathew S, Shah J, Banfield C, Hollingshead B, Steyn S, Osgood S, Beaumont K, Kainz S, Holecek C, Trausinger G, Raml R, Birngruber T
Comparative Study of Dermal Pharmacokinetics Between Topical Drugs Using Open Flow Microperfusion in a Pig Model
Health
2024

Cutaneous pharmacokinetics-based bioequivalence: A clinical dermal open flow microperfusion verification study using lidocaine and prilocaine combination topical products

Autor*innen: Tiffner, K. I., Ramezanli, T., Boulgaropoulos, B., Birngruber, T., Bodenlenz, M., Lackner, B. C., Raml, R., Jiang, Y., Raney, S. G., & Sinner, F.
Cutaneous pharmacokinetics-based bioequivalence: A clinical dermal open flow microperfusion verification study using lidocaine and prilocaine combination topical products
Health
2023

Quantification of the Therapeutic Antibody Ocrelizumab in Mouse Brain Interstitial Fluid Using Cerebral Open Flow Microperfusion and Simultaneous Monitoring of the Blood–Brain Barrier Integrity

Autor*innen: Altendorfer-Kroath, Thomas; Hummer, Joanna; Kollmann, Denise; Boulgaropoulos, Beate; Raml, Reingard; Birngruber, Thomas
Quantification of the Therapeutic Antibody Ocrelizumab in Mouse Brain Interstitial Fluid Using Cerebral Open Flow Microperfusion and Simultaneous Monitoring of the Blood–Brain Barrier Integrity
Health
2023

Small volume rapid equilibrium dialysis (RED) measures effects of interstitial parameters on the protein-bound fraction of topical drugs

Autor*innen: Wiltschko, Laura; Roblegg, Eva; Raml, Reingard; Birngruber, Thomas
Small volume rapid equilibrium dialysis (RED) measures effects of interstitial parameters on the protein-bound fraction of topical drugs
Health
2022

Assessment of Two Different Glucagon Assays in Healthy Individuals and Type 1 and Type 2 Diabetes Patients

Autor*innen: Brunner, Martina; Moser, Othmar; Raml, Reingard; Haberlander, Maximilian; Boulgaropoulos, Beate; Obermayer-Pietsch, Barbara; Svehlikova, Eva; Pieber, Thomas R.; Sourij, Harald
Assessment of Two Different Glucagon Assays in Healthy Individuals and Type 1 and Type 2 Diabetes Patients
Health
2022

Effect of Liraglutide Treatment on Whole-body Glucose Fluxes in C-peptide–Positive Type 1 Diabetes During Hypoglycemia

Autor*innen: Zenz, Sabine; Regittnig, Werner1; Boulgaropoulos, Beate; Augustin, Thomas; Brunner, Martina; Korsatko, Stefan; Münzker, Julia; Narath, Sophie H.; Raml, Reingard; Magnes, Christoph; Pieber, Thomas R
Effect of Liraglutide Treatment on Whole-body Glucose Fluxes in C-peptide–Positive Type 1 Diabetes During Hypoglycemia
Health
2022

Chronic Inflammation Might Protect Hemodialysis Patients From Severe COVID-19

Autor*innen: Prietl, Barbara; Odler, Balazs; Kirsch, Alexander H.; Artinger, Katharina; Eigner, Manfred; Schmaldienst, Sabine; Pfeifer, Verena; Stanzer, Stefanie; Eberl, Anita; Raml, Reingard; Pieber, Thomas; Rosenkranz, Alexander R.; Brodmann, Marianne; Eller, Philipp; Eller, Kathrin
Chronic Inflammation Might Protect Hemodialysis Patients From Severe COVID-19
Health
2021

Comparative in vitro release testing (IVRT) of acyclovir products

Autor*innen: Katrin I. Tiffner, Isadore Kanfer, Thomas Augustin, Reingard Raml, Sam G. Raney, Frank Sinner
Comparative in vitro release testing (IVRT) of acyclovir products
Health
2020

OFM recirculation and OFM suction: Advanced in-vivo open flow microperfusion methods for direct and absolute quantification of albumin in interstitial fluid

Autor*innen: Hummer, Joanna; Schwingenschuh, Simon; Raml, Reingard; Boulgaropoulos, Beate; Schwagerle, Gerd; Augustin, Thomas; Sinner, Frank; Birngruber, Thomas
OFM recirculation and OFM suction: Advanced in-vivo open flow microperfusion methods for direct and absolute quantification of albumin in interstitial fluid
Health
2019

Comparison of cerebral Open Flow Microperfusion and Microdialysis when sampling small lipophilic and small hydrophilic substances

Autor*innen: Altendorfer-Kroath, Thomas; Schimek, Denise; Eberl, Anita; Rauter, Günther; Ratzer, Maria; Raml, Reingard; Sinner, Frank; Birngruber, Thomas
Comparison of cerebral Open Flow Microperfusion and Microdialysis when sampling small lipophilic and small hydrophilic substances
Health
2019

The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species

Autor*innen: Carmona-Gutierrez, Didac; Zimmermann, Andreas; Kainz, Katharina; Pietrocola, Federico; Chen, Guo; Maglioni, Silvia; Schiavi, Alfonso; Nah, Jihoon; Mertel, Sara; Beuschel, Christine B.; Castoldi, Francesca; Sica, Valentina; Trausinger, Gert; Raml, Reingard; Sommer, Cornelia; Schroeder, Sabrina; Hofer, Sebastian J.; Bauer, Maria A.; Pendl, Tobias; Tadic, Jelena; Dammbrueck, Christopher; Hu, Zehan; Ruckenstuhl, Christoph; Eisenberg, Tobias; Durand, Sylvere; Bossut, Noélie; Aprahamian, Fanny; Abdellatif, Mahmoud; Sedej, Simon; Enot, David P.; Wolinski, Heimo; Dengjel, Jörn; Kepp, Oliver; Magnes, Christoph; Sinner, Frank M.; Pieber, Thomas R.; Sadoshima, Junichi; Ventura, Natascia; Sigrist, Stephan J.; Kroemer, Guido; Madeo, Frank
The flavonoid 4,4′-dimethoxychalcone promotes autophagy-dependent longevity across species
Health
2018

A comprehensive approach to qualify and validate the essential parameters of an in vitro release test (IVRT) method for acyclovir cream, 5%

Autor*innen: Tiffner, Katrin Irene; Kanfer, Isadore; Augustin, Thomas; Raml, Reingard; Raney, Sam G.; Sinner, Frank M.
A comprehensive approach to qualify and validate the essential parameters of an in vitro release test (IVRT) method for acyclovir cream, 5%
Health
2018

Impact of C-Peptide Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycaemia in T1D.

Autor*innen: Zenz, Sabine; Mader, Julia K; Regittnig, Werner; Brunner, Martina; Korsatko, Stefan; Boulgaropoulos, Beate; Magnes, Christoph; Raml, Reingard; Narath, Sophie H.; Eller, Philipp; Augustin, Thomas; Pieber, Thomas R
Impact of C-Peptide Status on the Response of Glucagon and Endogenous Glucose Production to Induced Hypoglycaemia in T1D.
Health
2018

Quantification of acyclovir in dermal interstitial fluid and human serum by ultra-high-performance liquid-high-resolution tandem mass spectrometry for topical bioequivalence evaluation

Autor*innen: Schimek, Denise; Raml, Reingard; Francesconi, Kevin A.; Bodenlenz, Manfred; Sinner, Frank
Quantification of acyclovir in dermal interstitial fluid and human serum by ultra-high-performance liquid-high-resolution tandem mass spectrometry for topical bioequivalence evaluation
Health
2017

Assessment of skin permeability to topically applied drugs by skin impedance and admittance.

Autor*innen: Schwingenschuh, Simon; Scharfetter, Hermann; Martinsen, Orjan Grottem; Boulgaropoulos, Beate; Augustin, Thomas; Tiffner, Katrin Irene; Dragatin, Christian; Raml, Reingard; Hoefferer, Christian; Prandl, Eva-Christina; Sinner, Frank M.; Hajnsek, Martin
Assessment of skin permeability to topically applied drugs by skin impedance and admittance.
Health
2017

Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence

Autor*innen: Bodenlenz, Manfred; Tiffner, Katrin Irene; Raml, Reingard; Augustin, Thomas; Dragatin, Christian; Birngruber, Thomas; Schimek, Denise; Schwagerle, Gerd; Pieber, Thomas R.; Raney, Sam G.; Kanfer, Isadore; Sinner, Frank
Open Flow Microperfusion as a Dermal Pharmacokinetic Approach to Evaluate Topical Bioequivalence
Health
2016

Matrix removal in state of the art sample preparation methods for serum by charged aerosol detection and metabolomics-based LC-MS

Autor*innen: Schimek, Denise; Francesconi, Kevin A.; Mautner, Anton; Libiseller, Gunnar; Raml, Reingard; Magnes, Christoph
Matrix removal in state of the art sample preparation methods for serum by charged aerosol detection and metabolomics-based LC-MS
Health
2016

Kinetics of Clobetasol-17-Propionate in Psoriatic Lesional and Non-Lesional Skin Assessed by Dermal Open Flow Microperfusion with Time and Space Resolution

Autor*innen: Bodenlenz, Manfred; Dragatin, Christian; Liebenberger, Lisa; Tschapeller, Bernd; Boulgaropoulos, Beate; Augustin, Thomas; Raml, Reingard; Gatschelhofer, Christina; Wagner, Nathalie; Benkali, Khaled; Rony, Francois; Pieber, Thomas; Sinner, Frank
Kinetics of Clobetasol-17-Propionate in Psoriatic Lesional and Non-Lesional Skin Assessed by Dermal Open Flow Microperfusion with Time and Space Resolution
Health
2016

Determination of (2)H-enrichment of rat brain interstitial fluid and rat plasma by headspace-gas-chromatography - quadrupole-mass-spectrometry

Autor*innen: Eberl, A; Altendorfer‐Kroath, Thomas; Kollmann, D; Birngruber, Thomas; Sinner, F; Raml, R; Magnes, Christoph
Determination of (2)H-enrichment of rat brain interstitial fluid and rat plasma by headspace-gas-chromatography - quadrupole-mass-spectrometry
Health
2014

Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx,®/Doxil®—A Cerebral Open Flow Microperfusion Pilot Study

Autor*innen: Birngruber, Thomas; Raml, Reingard; Gladdines, Werner; Gatschelhofer, Christina; Gander, Edgar; Ghosh, Arijit; Kroath, Thomas; Gaillard, Pieter J; Pieber, Thomas R; Sinner, Frank
Enhanced Doxorubicin Delivery to the Brain Administered Through Glutathione PEGylated Liposomal Doxorubicin (2B3-101) as Compared with Generic Caelyx,®/Doxil®—A Cerebral Open Flow Microperfusion Pilot Study
Zu allen Publikationen

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